Which observation is key in a physical examination related to end-of-life signs?

Corneal clouding is a significant observation during a physical examination at the end of life because it often indicates a decline in physiological functions. As a person approaches death, bodily systems begin to shut down, and one of the visible signs can be changes in the eyes, including corneal clouding. This clouding can result from dehydration and decreased circulation, signaling that the body's organs are failing. Recognizing this sign is crucial as it helps healthcare providers and caregivers understand the patient's status and prepare for appropriate end-of-life care.

While assessing pulse rate, temperature, and respiration rate are important components of a physical examination, they do not specifically signify the end-of-life transition as clearly as corneal clouding does. Pulse and respiration can fluctuate due to various conditions and are less definitive indicators, while temperature changes may occur but do not carry the same weight in this context.